Name | 19-nortestosterone |
Synonyms | NADROLONE Nandrolone Nandrolone Base 19-NORTESTOSTERONE 19-nortestosterone 19-NORANDROSTENOLONE 17-hydroxyestr-4-en-3-one 17b-hydroxyestra-4-en-3-one 17BETA-HYDROXY-4-ESTREN-3-ONE 17-beta-hydroxyoestr-4-en-3-one (17beta)-17-hydroxyestr-4-en-3-one 19-nortestosterone standard solution 19-nortestosterone--dea schedule iii 17BETA-HYDROXY-19-NORANDROST-4-EN-3-ONE 17-HYDROXY-13-METHYL-2,6,7,8,9,10,11,12,14,15,16,17-DODECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE, 5-ANDROSTENEDIONE |
CAS | 434-22-0 |
EINECS | 207-101-0 |
InChI | InChI=1/C18H26O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-17,20H,2-9H2,1H3 |
InChIKey | NPAGDVCDWIYMMC-IZPLOLCNSA-N |
Molecular Formula | C18H26O2 |
Molar Mass | 274.4 |
Density | 1.0528 (rough estimate) |
Melting Point | 120-125°C |
Boling Point | 357.38°C (rough estimate) |
Specific Rotation(α) | D22 +55° (c = 0.93 in chloroform) |
Flash Point | 2℃ |
Water Solubility | 3.09g/L(25 ºC) |
Vapor Presure | 2.25E-09mmHg at 25°C |
Color | Dimorphic crystals from CH2Cl2/Et2O |
Merck | 6365 |
BRN | 2055849 |
pKa | 15.06±0.40(Predicted) |
Storage Condition | Controlled Substance, -20°C Freezer |
Refractive Index | 1.4800 (estimate) |
Use | Used as sports nutrition health products |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R64 - May cause harm to breast-fed babies R40 - Limited evidence of a carcinogenic effect R61 - May cause harm to the unborn child R60 - May impair fertility R36 - Irritating to the eyes R11 - Highly Flammable R38 - Irritating to the skin R19 - May form explosive peroxides |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S53 - Avoid exposure - obtain special instructions before use. S16 - Keep away from sources of ignition. |
UN IDs | UN 1648 3 / PGII |
WGK Germany | 3 |
RTECS | KG7964000 |
HS Code | 29372900 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
detection | nandrolone has strong toxic side effects, which can cause cancer, hepatitis and nerve disorder. The malicious incorporation of nandrolone in functional food can easily cause harm to human body, so it is of great significance to detect nandrolone in functional food. Because the addition of 17 β-nt in the functional food is very small, and the composition of the functional food is generally complex, the matrix effect is difficult to eliminate, and the conventional detection method is difficult to achieve the ideal detection effect, therefore, it is urgent to establish an economical, reliable, specific, sensitive, rapid and effective method. Research has developed a method for the preparation of artificial haptens, antigens and antibodies that retain the structure of Nandrolone to the greatest extent, the nandrolone hapten prepared by chemical synthesis method was linked with the carrier BSA protein to synthesize artificial antigen, and the antibody was prepared by immunizing the artificial antigen, taking blood, separating antiserum and purifying it. The present invention is to design and synthesize a hapten and an artificial antigen with nandrolone structure, which highlights the molecular specific antigenic determinant and overcomes the difficulty of chemical synthesis, and the use of immune animals to induce antibodies with high affinity; Compared with other similar methods, with specific, sensitive, accurate, fast, convenient, cheap and so on, the synthesis of hapten laid the foundation for the preparation of antibodies with good specificity. |
drug-related effects | 1) can enhance the anticoagulant effects of anticoagulant drugs coumarin and warfarin; 2) combined with corticosteroids, can increase blood sugar. |
Use | for sports nutrition |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |